Author

Lujia Chen

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:differential expression· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Anchen QiuiD· 2 shared Xinghua LuiD· 2 shared Alicia N. RizzoiD· 1 shared Amy Zhao· 1 shared Binfeng LuiD· 1 shared Boyang Sun· 1 shared Bryan Andrews· 1 shared Charles S Dela Cruz· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Anchen QiuORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Circuit regulation along an activity continuum shapes flexible and stable representations during learning

Daniel Yusufi, Yan Ma, Lujia Chen, Garret Wang, Taylor Malone, Kai Zhang, June Hoan Kim, Farid Shahid, Kyle Cekada, Ellane Barcelone, Yi Gu

The paper identifies mechanisms in the medial entorhinal cortex that balance representational flexibility and stability during learning through excitatory and inhibitory neuronal activity dynamics.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience

A Time-Resolved Single-Cell Atlas Reveals Infection-Status, Age-, and Sex-Dependent Immune Responses Drive Viral Disease Severity

Lujia Chen, Anchen Qiu, JooYoung Kim, Nebal Abu Hussein, Mengyao Lu, Karen Agaronyan, Kexin Sun, Yifan Yuan, Amy Zhao, Gagan Heda, Xinghua Lu, Georgios D. Kitsios, Alicia N. Rizzo, William Bain, Toru Nyunoya, , Lokesh Sharma

This study uses time-resolved single-cell RNA sequencing in mice to show age and sex influence immune responses and viral disease severity through altered gene expression and inflammation.

bioRxiv · Aug 11, 2026 · PreprintImmunology

Causal Modeling Reveals Cell-Cell Communication Dynamics in the Tumor Microenvironment During Anti-PD-1 Therapy in Breast Cancer Patients

Anchen Qiu, Han Zhang, Joseph Ramsey, Bryan Andrews, Boyang Sun, Shuangxia Ren, Meng‐Yao Lu, Kun Zhang, Gregory F. Cooper, Binfeng Lu, Lujia Chen, Xinghua Lu

This study uses single-cell RNA-seq data to analyze cell-cell communication changes in breast cancer patients during anti-PD-1 therapy, identifying key pathways and potential therapeutic targets.

Briefings in Bioinformatics · Mar 1, 2026Peer-reviewedBioinformatics