Generation of Mouse-Zebrafish Hematopoietic Tissue Chimeric Embryos for Hematopoiesis and Host-Pathogen Interaction Studies
Margarita Parada-Kusz, Anne E. Clatworthy, Elliott J. Hagedorn, Cristina Peñaranda, Anil V. Nair, Jonathan E. Henninger, Christoph M. Ernst, Brian Li, Raquel Riquelme, Humberto B. Jijon, Eduardo J. Villablanca, Leonard Ira Zon, Deborah Tan Hung, Miguel L. Allende
This study xenografts murine bone marrow cells into zebrafish embryos to study hematopoiesis and host-pathogen interactions, showing successful integration and immune response.
Disease Models & Mechanisms · Sep 28, 2018Peer-reviewedDevelopmental Biology