Author

Mei Hua Jiang

Augusta UniversityORCID 0000-0002-9111-0410Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Hedong LiiD· 3 shared Brendan Puls· 2 shared Christine Williams· 2 shared Natalie Mseis-JacksoniD· 2 shared Xuanyu CheniD· 2 shared Alice CaiiD· 1 shared Arya Ranchod· 1 shared Austin Redilla· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersNeuroscience

Hedong LiORCID

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3 papers

Recent·Most cited

Dynamic regulation of NeuroD1 expression level by a novel viral construct during astrocyte-to-neuron reprogramming

Natalie Mseis-Jackson, Mei Hua Jiang, Mehek Sharma, Arya Ranchod, Christine Williams, Xuanyu Chen, Hedong Li

This study introduces a viral construct that dynamically regulates NeuroD1 expression during astrocyte-to-neuron reprogramming, reducing its level in reprogrammed neurons to enhance GABAergic differentiation.

Molecular Therapy — Nucleic Acids · Sep 5, 2025Peer-reviewedNeuroscience

MicroRNA-375 is induced during astrocyte-to-neuron reprogramming and promotes survival of reprogrammed neurons when overexpressed

Xuanyu Chen, Ivan Sokirniy, Xin Wang, Mei Hua Jiang, Natalie Mseis-Jackson, Christine Williams, Kristopher Mayes, Na Jiang, Brendan Puls, Quansheng Du, Yang Shi, Hedong Li

This study identifies miR-375 as a factor that enhances astrocyte-to-neuron reprogramming by promoting cell survival during the process.

Cells · Sep 3, 2023Peer-reviewedNeuroscience

Regeneration of dorsal spinal cord neurons after injury via in situ NeuroD1-mediated astrocyte-to-neuron conversion

Brendan Puls, Yan Ping Ding, Fengyu Zhang, Mengjie Pan, Zhuofan Lei, Zifei Pei, Mei Hua Jiang, Yuting Bai, Cody Forsyth, Morgan Metzger, Tanvi Rana, Lei Zhang, Xiaoyun Ding, Matthew G. Keefe, Alice Cai, , Gong Chen

This study demonstrates efficient regeneration of dorsal spinal cord neurons from reactive astrocytes after injury using NeuroD1-mediated in vivo reprogramming via AAV.

Frontiers in Cell and Developmental Biology · Dec 16, 2020Peer-reviewedNeuroscience