Author
Children's Hospital of PhiladelphiaORCID 0000-0003-0038-318XUnclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Alyssa Baccarella, Yusen Zhou, Tatiana A. Karakasheva…·Melanie A. Ruffner
The paper uses scRNA-seq to compare IL-13-treated esophageal organoids with EoE biopsies, revealing shared cell state heterogeneity and differentiation hierarchy dysregulation.
Tatiana A. Karakasheva, Clara Morral, Yusen Zhou…·Kathryn E. Hamilton
The paper identifies an inflammatory secretory progenitor cell state in Crohn's disease patients and shows its epigenetic regulation in stem cells.
Xianghui Ma, Noor B. Dawany, Ayano Kondo…·Kathryn E. Hamilton
This study investigates the role of TNFSF13 in colonic epithelial cell-B cell interactions and finds that TNFSF13 insufficiency disrupts B cell differentiation and epithelial growth.
Aleksejs Sazonovs, Christine R. Stevens, Guhan Ram Venkataraman…·Rasha Shawky
The paper identifies ten new genes with coding variants linked to Crohn's disease risk using sequencing data from over 30,000 patients and 80,000 controls.