Teresa Mendes Maia

The paper uses proteomics to show increased ECM remodeling and complement activation in cardiac ATTR amyloidosis.

ProteoBench provides a centralized platform for comparing proteomics data analysis workflows, enabling benchmarking and community collaboration.

This study harmonizes quality controls across proteomics core facilities to improve data comparability and reliability through a 4-year longitudinal dataset and common processing software.

The paper introduces a dual-column electrospray source for nano-flow proteomics to improve throughput while maintaining sensitivity in low-input samples.

This study integrates proteomics, transcriptomics, and metabolomics data from IEM patients to identify perturbed protein complexes and pathways, highlighting mitochondrial oxidative phosphorylation and histone acetylation dysregulation.

This study benchmarks 12 DIA analysis workflows for shotgun proteomics samples, finding DIA-NN and Spectronaut in library-free mode offer highest sensitivity with good reproducibility and accuracy.

The paper shows androgen-regulated ESRP2 transcription controls alternative splicing in prostate cancer, with implications for metastasis.

This study shows that Parl deficiency in mice leads to mitochondrial dysfunction, Complex III defects, and Leigh-like syndrome, highlighting its critical role in neurological health.