Author

Mario P. Colombo

Fondazione IRCCS Istituto Nazionale dei TumoriORCID 0000-0003-0042-7955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Elena JachettiiD· 2 shared Antonino BelfioreiD· 1 shared Benedetto GrimaldiiD· 1 shared Cheryl A. HawkesiD· 1 shared Claudia ChiodoniiD· 1 shared Claudio TripodoiD· 1 shared Daniele LecisiD· 1 shared Davide PerniciiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

Elena JachettiORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 1, 2026

ENPP3 expressed by HER2-positive breast cancer cells is associated with good prognosis by restraining epithelial-to-mesenchymal phenotype

Roberta Bongiorno, Maria Teresa Majorini, Valeria Figa'…·Daniele Lecis

This study shows that ENPP3 expression in HER2-positive breast cancer cells is linked to better prognosis by inhibiting epithelial-to-mesenchymal transition.

DOI 10.64898/2026.08.31.747828

mousehuman

𝕏 PostBluesky

Pharmacology & ToxicologyEpigenomicsPeer-reviewedJan 29, 2025

EZH2 inhibition enhances the activity of platinum chemotherapy in aggressive variant prostate cancer

Maryam Latarani, Perla Pucci, Mark Eccleston…·Francesco Crea

This study shows that EZH2 inhibition enhances platinum chemotherapy effectiveness in aggressive variant prostate cancer by reducing H3K27me3 and modulating DNA repair and apoptosis pathways.

6 citations

humanbulk RNA-seq

𝕏 PostBluesky