Author

Meenakshi Malik

Albany College of Pharmacy and Health SciencesORCID 0000-0003-0051-4485Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Assay:metagenomics· 1

Frequent Co-Authors

Chandra Shekhar BakshiiD· 3 shared Zhuo MaiD· 3 shared Anthony Centone· 1 shared Anthony J. CentoneiD· 1 shared Jacob Miller· 1 shared Kayla Marie Fantone· 1 shared Matthew G. HiggsiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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3 shared papersMicrobiology

Chandra Shekhar BakshiORCID

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3 papers

Recent·Most cited

ImmunologyInfection and ImmunityPeer-reviewedSep 15, 2026

Antioxidant defenses of Francisella tularensis perturb Aim2 Inflammasome Activation

Zhuo Ma, Jacob Miller, Kayla Marie Fantone…·Meenakshi Malik

This study shows that F. tularensis modulates the macrophage redox environment to suppress Aim2 inflammasome activation, revealing a mechanism by which it evades host immune responses.

DOI 10.1128/iai.00453-26

mouseproteomics

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MicrobiologybioRxivPreprintMay 8, 2026

Control of Oxidative Stress and Intracellular Survival in Francisella tularensis Live Vaccine Strain (LVS) via Acyl-CoA Synthetase

Anthony Centone, Zhuo Ma, Meenakshi Malik, Chandra Shekhar Bakshi

This study identifies FTL_0690 as an acyl-CoA synthetase critical for lipid homeostasis, membrane integrity, and oxidative stress resistance in F. tularensis LVS.

DOI 10.64898/2026.05.08.723735

experimental assaycell type annotation

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MicrobiologyJournal of BacteriologyPeer-reviewedSep 3, 2025

Role of Thioredoxin Reductase (TrxB) in Oxidative Stress Response of Francisella tularensis Live Vaccine Strain

Matthew G. Higgs, Zhuo Ma, Anthony J. Centone…·Meenakshi Malik

This study investigates the role of thioredoxin reductase (TrxB) in oxidative stress resistance and intramacrophage survival in Francisella tularensis.

DOI 10.1128/jb.00173-25

bacteria (other)experimental assay

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