Michelle L. Pleet

The paper identifies extracellular vesicles (sEVs) from EBV-transformed B-cells as a vehicle for exporting host DNA and EBV EBER1 RNA, linking peripheral EBV infection to distal tissue signaling in MS.

This paper identifies EV-associated cytokines as mediators of IVIg activity, showing that engineered IFNγ-eEVs can suppress IFNγ signaling through context-dependent mechanisms.

The paper develops RPSPASS, a software tool for automated analysis of microfluidic nanoparticle data, improving accuracy, ergonomics, and reporting transparency.

This study identifies an HIV-1 antisense transcript that enforces latency by inducing epigenetic silencing and blocks latency reversal in CD4+ T-cells.