Author

Sogol Sedighi

Johns Hopkins UniversityORCID 0000-0003-0136-5821Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

D. Brian FosteriD· 3 shared Brian P O'RourkeiD· 2 shared Robert N. O’MeallyiD· 2 shared Aashik Bhalodia· 1 shared Abhishek VatsiD· 1 shared Biyi LiiD· 1 shared Carolina DuqueiD· 1 shared Charles D. CoheniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

D. Brian FosterORCID

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3 papers

Recent·Most cited

BiochemistrybioRxivPreprintJul 29, 2026

SureQuant IS-PRM Enables Cross-Species Targeted Quantification of Retinoid Metabolism and Signaling Proteins in the Heart

Sogol Sedighi, Robert N. O’Meally, Sunayana Begum Syed…·D. Brian Foster

The paper develops a targeted proteomics method to quantify retinoid metabolism and signaling proteins across species and tissues, revealing tissue-specific networks and developmental changes in the heart.

DOI 10.64898/2026.07.27.741027

mouserat

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Molecular BiologyACS OmegaPeer-reviewedAug 6, 2025

Inhibition of Cardiac p38 Highlights the Role of the Phosphoproteome in Heart Failure Progression

Sogol Sedighi, Ting Liu, Robert N. O’Meally…·D. Brian Foster

This study investigates the effects of p38 MAPK inhibition on cardiac remodeling in a guinea pig HF model, finding that SB203580 treatment protects cardiac function and phosphoproteome integrity.

3 citations

proteomicsstatistical model

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ImmunologybioRxivPreprintMay 8, 2024

Splenic follicular B cells promote adverse cardiac remodeling after myocardial infarction via MHC II-dependent antigen presentation.

Obialunanma V. Ebenebe, Jana P. Lovell, Carolina Duque…·Luigi Adamo

This study shows splenic follicular B cells worsen heart failure after MI by presenting cardiac antigens via MHC II, promoting adverse cardiac remodeling.

3 citations

mousehuman

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