Michelle M. Halstead

The paper identifies genetic variants in 30 families with unexplained euploid pregnancy loss, finding monogenic causes in 25% of cases and expanding understanding of early human lethality.

This study shows that maternal Med12 is essential for trophoblast pluripotency and placental development, with loss leading to placental malformations and embryonic death.

The paper uses Oxford Nanopore long-read sequencing to annotate transcript isoforms in 19 chicken tissues, identifying novel transcripts and highlighting tissue-specific expression patterns.

This study profiles histone modifications during bovine preimplantation development, showing their role in gene regulation and lineage specification.

The paper profiles open chromatin in developing pig muscle to identify regulatory regions and provides a resource for genome regulation studies and variant filtering in pig breeding.

This study maps transcription initiation sites in 31 bovine tissues, revealing promoter activity, pervasive transcription, and tissue-specific promoter usage comparable to human and mouse.

The paper identifies and compares chromatin accessibility in cattle, pig, and mouse tissues using ATAC-seq, finding species-specific regulatory elements and conservation patterns.

The paper profiles accessible chromatin in bovine embryos to show species-specific regulation of genome activation, finding similarities between cattle and humans but differences from mice.