Author

Ian J. Molineux

The University of Texas at AustinORCID 0000-0003-0184-7652Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Organism:bacteria (other)· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein folding & dynamics· 1 Organism:virus· 1

Frequent Co-Authors

Huaxin YuiD· 2 shared Jian YueiD· 2 shared Jun LiuiD· 2 shared Chunyan Wang· 1 shared John J. MekalanosiD· 1 shared Justin ZhaoiD· 1 shared Muyuan CheniD· 1 shared Taehyun ParkiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Huaxin YuORCID

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2 papers

Recent·Most cited

Sequential assembly in vivo of the bacteriophage P22 genome translocation channel

Huaxin Yu, Jian Yue, Taehyun Park, Chunyan Wang, Muyuan Chen, Jun Liu, Ian J. Molineux

The paper determines the in vivo structures of P22 infection intermediates and explains how gp10 templates the sequential assembly of three proteins into a trans-envelope channel for genome translocation.

bioRxiv · Sep 9, 2026 · PreprintMicrobiology

Structural basis of multimodal adsorption and infection initiation by Vibrio phage Peru-2

Huaxin Yu, Justin Zhao, Jian Yue, Ian J. Molineux, Jun Liu, William Paul Robins, John J. Mekalanos

This study determines the structure of Vibrio phage Peru-2, revealing its multimodal adsorption strategy and infection mechanism involving tailspikes and interactions with bacterial surfaces.

bioRxiv · Jun 26, 2026 · PreprintMicrobiology