Author

Anne Zaremba

Essen University HospitalORCID 0000-0002-6932-0489Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:fine-mapping· 1 Research Focus:gene regulatory network inference· 1 Research Focus:GWAS / association mapping· 1

Frequent Co-Authors

Dirk SchadendorfiD· 2 shared Yevgeniy R. SemenoviD· 2 shared Aidan O’BrieniD· 1 shared Alan R. SandersiD· 1 shared Alex Stratigos· 1 shared Alexander Maxwell MenziesiD· 1 shared Amy A HutchinsoniD· 1 shared Andrew BakshiiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetic & Genomic Medicine

Dirk SchadendorfORCID

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2 papers

Recent·Most cited

Melanoma germline genetics: immune, cancer driver, and Wnt signaling genes

G J M Shanika R Jayasinghe, Jianxin Shi, Rohit Thakur, Rebecca Ivy Hartman, Huanwei Wang, Phuc H. Hoang, Daniel R. Dochtermann, Samuel Anyaso-Samuel, Mathias Seviiri, Quan Hoang Nguyen, P. Prakrithi, Thi-Van-Trinh Tran, Xiaoyu Wang, Mai Xu, Xing Hua, , Nhan Do

This paper identifies 116 risk loci for melanoma through GWAS, links susceptibility to immunity and Wnt signaling, and develops a PRS improving risk prediction.

medRxiv · Oct 15, 2026 · PreprintGenetic & Genomic Medicine

Multiomic profiling of a unique in-transit melanoma cohort identifies melanoma differentiation as predictor of tumor progression and therapy response

Giuseppe Tarantino, Anne Zaremba, Tuulia Vallius, Mark Woodnorth, Yichao Hua, Roxanne J. Pelletier, Mariana Lopez Leon, Yingxiao Shi, Zoltan Maliga, Samira Makhzami, Tyler J. Aprati, Bojan Karlaš, Valerie Glutsch, Bastian Schilling, Jessica C. Hassel, , Dirk Schadendorf

The paper identifies melanoma differentiation and immune exhaustion as predictors of tumor progression and therapy response in in-transit melanoma patients through multiomic profiling.

bioRxiv · Oct 1, 2025 · PreprintCancer Biology