Author

Josue Alan Lopez

University of IowaORCID 0000-0003-0232-4407Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

Amy LeeiD· 2 shared Joseph T. VecchiiD· 2 shared Albina Tskhay· 1 shared Alec EamesiD· 1 shared Alexander TyshkovskiyiD· 1 shared Alexey V. TerskikhiD· 1 shared Alibek MoldakozhayeviD· 1 shared Andrei E. TarkhoviD· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersNeuroscience

Amy LeeORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Systems BiologybioRxivPreprintSep 30, 2026

Aged white adipose tissue is rejuvenated in a young host through thermogenic remodeling of mature adipocytes

Alibek Moldakozhayev, Alexander Tyshkovskiy, Pasquale Nigro…·Vadim N. Gladyshev

This study shows that old white adipose tissue can rejuvenate in young hosts through thermogenic remodeling and pathway activation, reversing biological age markers.

DOI 10.64898/2025.12.28.696721

mousebulk RNA-seq

𝕏 PostBluesky

NeuroscienceJournal of Neuroscience MethodsPeer-reviewedSep 1, 2021

NeuriteNet: A Convolutional Neural Network for determining morphological differences in neurite growth

Joseph T. Vecchi, Sean Mullan, Josue Alan Lopez…·Amy Lee

NeuriteNet is a CNN that sorts neuronal images into control and treatment groups based on morphological differences and highlights distinguishing features via saliency maps.

15 citations

mouseimaging

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NeurosciencebioRxivPreprintJul 26, 2021

Caldendrin represses neurite regeneration via a sex-dependent mechanism in sensory neurons

Josue Alan Lopez, Annamarie Yamamoto, Joseph T. Vecchi…·Amy Lee

This study shows caldendrin inhibits neurite regeneration in dorsal root ganglion neurons, with a sex-dependent effect on Cav1 channel regulation.

1 citation

mouseexperimental assay

𝕏 PostBluesky