Author

Amanda M. Dudek

Stanford MedicineORCID 0000-0003-0239-3576Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:genetic perturbation / CRISPR· 2 Organism:human· 2 Assay:CRISPR screen· 1 Assay:proteomics· 1

Frequent Co-Authors

Hana Y. GhanimiD· 2 shared Kaya Ben-Efraim· 2 shared Matthew Hebden PorteusiD· 2 shared Nicole M. Johnston· 2 shared Sofia E. LunaiD· 2 shared William N. FeistiD· 2 shared Alvaro AmoriniD· 1 shared Ashley UtziD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersBioengineering

Hana Y. GhanimORCID

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2 papers

Recent·Most cited

Engineering hematopoietic stem and progenitor cells to generate red blood cells as viral traps against HIV-1

Sofia E. Luna, William N. Feist, Kaya Ben-Efraim, Michael A. Pendergast, Freja K. Ekman, Britney N. Hernandez, Megan E. Merritt-Garza, Kathleen Romero, Zak Kostamo, Nelson A. Amorin, Nicole M. Johnston, Hana Y. Ghanim, Vivien Sheehan, Amanda M. Dudek, Matthew Hebden Porteus

This paper engineers hematopoietic stem and progenitor cells to express CD4 on red blood cells, creating viral traps to neutralize HIV-1.

Molecular Therapy Advances · Sep 10, 2026Peer-reviewedBioengineering

Combining Cell-Intrinsic and -Extrinsic Resistance to HIV-1 By Engineering Hematopoietic Stem Cells for CCR5 Knockout and B Cell Secretion of Therapeutic Antibodies

William N. Feist, Sofia E. Luna, Kaya Ben-Efraim, Maria V. Filsinger Interrante, Alvaro Amorin, Nicole M. Johnston, Theodora U. J. Bruun, Ashley Utz, Hana Y. Ghanim, Benjamin J. Lesch, Theresa M. McLaughlin, Amanda M. Dudek, Matthew Hebden Porteus

This paper describes engineering hematopoietic stem cells to produce CCR5 knockout cells and secrete HIV-1 inhibiting antibodies, aiming for a one-time cure for HIV-1.

Nature Communications · Mar 31, 2025Peer-reviewedBioengineering