Author

Alvaro Amorin

Institute for Stem Cell Biology and Regenerative MedicineORCID 0000-0002-3500-5085Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:flow cytometry· 1 Approach:genetic perturbation / CRISPR· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Matthew Hebden PorteusiD· 2 shared Aditi AgrawaliD· 1 shared Amanda M. DudekiD· 1 shared Ashley UtziD· 1 shared Benjamin J. LeschiD· 1 shared Esmond LeeiD· 1 shared Hana Y. GhanimiD· 1 shared Hannah FungiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Matthew Hebden PorteusORCID

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2 papers

Recent·Most cited

Immune Composition of the Mononuclear Cell Fraction of Human Umbilical Cord Blood

Karen Kikuta, Esmond Lee, Talia Menezes, Hannah Fung, Alvaro Amorin, Aditi Agrawal, Theodore L. Roth, Matthew Hebden Porteus

This study characterizes the immune subset composition of umbilical cord blood mononuclear cells and compares them to adult peripheral blood, revealing distinct immune profiles and developmental trends.

Frontiers in Immunology · Aug 1, 2025Peer-reviewedImmunology

Combining Cell-Intrinsic and -Extrinsic Resistance to HIV-1 By Engineering Hematopoietic Stem Cells for CCR5 Knockout and B Cell Secretion of Therapeutic Antibodies

William N. Feist, Sofia E. Luna, Kaya Ben-Efraim, Maria V. Filsinger Interrante, Alvaro Amorin, Nicole M. Johnston, Theodora U. J. Bruun, Ashley Utz, Hana Y. Ghanim, Benjamin J. Lesch, Theresa M. McLaughlin, Amanda M. Dudek, Matthew Hebden Porteus

This paper describes engineering hematopoietic stem cells to produce CCR5 knockout cells and secrete HIV-1 inhibiting antibodies, aiming for a one-time cure for HIV-1.

Nature Communications · Mar 31, 2025Peer-reviewedBioengineering