Author

Gregory D. Van Duyne

University of PennsylvaniaORCID 0000-0003-0247-1626Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

Kushol GuptaiD· 2 shared Ben E. BlackiD· 1 shared Frederic D. BushmaniD· 1 shared Joseph E. CurtisiD· 1 shared Kathryn Lorenz SarachaniD· 1 shared Mikkel Killingmoe Christensen· 1 shared Nicklas SappiD· 1 shared Nikolina SekulićiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

Kushol GuptaORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedMar 4, 2026

Structures of Nucleotide-Bound Redondovirus Rep Protein Link Conformation and Function

Saira Montermoso, Kushol Gupta, Ruth A. Pumroy…·Gregory D. Van Duyne

This study presents the first structures of a Redondovirus Rep protein, revealing conformational changes linked to its helicase and endonuclease functions during viral DNA replication.

DOI 10.1371/journal.ppat.1013997

humancryo-EM

𝕏 PostBluesky

BiophysicsChromosome ResearchPeer-reviewedJun 11, 2025

Solution conformational differences between conventional and CENP-A nucleosomes are accentuated by reversible deformation under high pressure

Kushol Gupta, Nikolina Sekulić, Praveen Kumar Allu…·Ben E. Black

This study compares conventional and CENP-A nucleosomes using high-pressure SAXS, revealing differences in their conformational stability and response to pressure.

2 citations

structural biologyexperimental assay

𝕏 PostBluesky