Author

Ruth A. Pumroy

University of PennsylvaniaORCID 0000-0002-6200-6083Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:protein structure prediction· 2

Frequent Co-Authors

Vera Y. Moiseenkova‐BelliD· 2 shared Apala ChaudhuriiD· 1 shared Chloe Wang· 1 shared Daniel H. HwangiD· 1 shared Frederic D. BushmaniD· 1 shared Gregory D. Van DuyneiD· 1 shared Julia N. DanoniD· 1 shared Kimia Dasteh GoliiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

Vera Y. Moiseenkova‐BellORCID

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2 papers

Recent·Most cited

MicrobiologyPLoS PathogensPeer-reviewedMar 4, 2026

Structures of Nucleotide-Bound Redondovirus Rep Protein Link Conformation and Function

Saira Montermoso, Kushol Gupta, Ruth A. Pumroy…·Gregory D. Van Duyne

This study presents the first structures of a Redondovirus Rep protein, revealing conformational changes linked to its helicase and endonuclease functions during viral DNA replication.

DOI 10.1371/journal.ppat.1013997

𝕏 PostBluesky

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedJan 9, 2025

CryoEM structure of an MHC-I/TAPBPR peptide bound intermediate reveals the mechanism of antigen proofreading

Yi Sun, Ruth A. Pumroy, Leena Mallik…·Nikolaos G. Sgourakis

The paper determines the cryo-EM structure of an MHC-I/TAPBPR peptide intermediate, revealing how antigen proofreading occurs through transient peptide interactions.

10 citations

𝕏 PostBluesky