Praveen Kumar Allu

This paper describes the creation of a 2 Mb human artificial chromosome (HAC) using a protein-only centromere seeding approach that bypasses genetic engineering of target cells.

This paper describes a method to rapidly assemble functional modules for human artificial chromosomes (HACs) that can be seeded with epigenetic centromere components.

This study compares conventional and CENP-A nucleosomes using high-pressure SAXS, revealing differences in their conformational stability and response to pressure.