Author

Nicholas Hoppe

University of California, San FranciscoORCID 0000-0003-0265-5337Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Aashish ManglikiD· 1 shared Christian B. BillesbølleiD· 1 shared Christian B. MacdonaldiD· 1 shared Darko MitroviciD· 1 shared Donovan D. TrinidadiD· 1 shared Eshan MehrotraiD· 1 shared Justin G. EnglishiD· 1 shared Lucie DelemotteiD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

Aashish ManglikORCID

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1 paper

Recent·Most cited

BiochemistryCellPeer-reviewedJan 2, 2025

Molecular basis of proton-sensing by G protein-coupled receptors

Matthew K. Howard, Nicholas Hoppe, Xi‐Ping Huang…·Aashish Manglik

The paper identifies proton-sensing mechanisms in GPCRs using cryo-EM and deep mutational scanning, revealing a network of residues rather than a single site for proton recognition.

84 citationstop 1%

humanstructural biology

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