Author

Eshan Mehrotra

Cornell UniversityORCID 0000-0003-3153-9570Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Aashish ManglikiD· 1 shared Ailong KeiD· 1 shared Amy Wei-Lun TsaiiD· 1 shared Christian B. BillesbølleiD· 1 shared Christian B. MacdonaldiD· 1 shared Christopher M. JerniganiD· 1 shared Darko MitroviciD· 1 shared Donovan D. TrinidadiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

Aashish ManglikORCID

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3 papers

Recent·Most cited

BiochemistryCellPeer-reviewedJan 2, 2025

Molecular basis of proton-sensing by G protein-coupled receptors

Matthew K. Howard, Nicholas Hoppe, Xi‐Ping Huang…·Aashish Manglik

The paper identifies proton-sensing mechanisms in GPCRs using cryo-EM and deep mutational scanning, revealing a network of residues rather than a single site for proton recognition.

84 citationstop 1%

humanstructural biology

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GenomicsPLoS GeneticsPeer-reviewedSep 3, 2021

Dynamic neurogenomic responses to social interactions and dominance outcomes in female paper wasps

Floria M. K. Uy, Christopher M. Jernigan, Natalie C. Zaba…·Michael J. Sheehan

The paper examines transcriptional responses in the central brain and optic lobe of female paper wasps after social interactions, finding stronger responses in the central brain and gene expression changes related to aggression and reproduction in losers.

27 citations

bulk RNA-seqstatistical model

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Molecular BiologySciencePeer-reviewedAug 12, 2021

Structural basis for target-site selection in RNA-guided DNA transposition systems

Jung-Un Park, Amy Wei-Lun Tsai, Eshan Mehrotra…·Elizabeth H. Kellogg

The paper uses cryo-EM to reveal how TnsC regulates target-site selection in CRISPR-associated transposition systems by transferring polarity information to the transposase.

78 citationstop 3%

experimental assay

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