Author
Centre Hospitalier de l’Université de MontréalORCID 0000-0003-0276-9262Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Christ Dominique Ngassaki Yoka, Jean-Philippe Goulet, Soumia Khalfi…·Petronela Ancuța
This study shows that inhibiting REV-ERBβ increases HIV-1 reactivation in CD4+ T-cells but limits virion spread.
Marco Aurelio Díaz-Salinas, Mehdi Benlarbi, Debashree Chatterjee…·James B. Munro
This paper shows HIV-1CRF01_AE Env frequently adopts an open conformation (State 2A) that is susceptible to ADCC, unlike clade A/B Envs which require anti-cluster A antibodies to reach this state.
Jonathan Richard, Michael W. Grunst, Ling Niu…·Andrés Finzi
This study shows that the CD4 mimetic CJF-III-288 enables anti-CoRBS antibodies to mediate ADCC by stabilizing an asymmetric open Env conformation.
Jonathan Richard, Gérémy Sannier, Li Zhu…·Andrés Finzi
The paper shows CD4 downregulation precedes Env expression in HIV-1-infected cells, making them resistant to non-neutralizing antibody-mediated ADCC.
Lorie Marchitto, Jonathan Richard, Jérémie Prévost…·Andrés Finzi
This paper combines three CD4-induced antibodies with a CD4-mimetic to achieve potent ADCC activity against HIV-1-infected cells.