Author

Christian Tiede

University of LeedsORCID 0000-0003-0280-4005Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:structural biology· 1

Frequent Co-Authors

Darren Charles TomlinsoniD· 2 shared Ajinkya RaoiD· 1 shared Alexander L. BreezeiD· 1 shared Alistair J. FieldingiD· 1 shared Amy L. TurneriD· 1 shared Anna Ah-San TangiD· 1 shared Antonio N. CalabreseiD· 1 shared Britta Petersen· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Darren Charles TomlinsonORCID

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2 papers

Recent·Most cited

Cell BiologyThe Journal of Cell BiologyPeer-reviewedFeb 20, 2025

Structural characterization and inhibition of the interaction between ch-TOG and TACC3

James Shelford, Selena G. Burgess, Elena V. Rostkova…·Stephen Royle

This study determines the structure of the ch-TOG-TACC3 interaction and shows that inhibiting it causes pericentriolar material fragmentation and delayed mitosis.

4 citations

structural biologyexperimental assay

𝕏 PostBluesky

Molecular BiologyNature CommunicationsPeer-reviewedJun 30, 2021

RAS-inhibiting biologics identify and probe druggable pockets including an SII-α3 allosteric site.

Katarzyna Z. Haza, Heather L. Martin, Ajinkya Rao…·Darren Charles Tomlinson

This paper identifies two RAS-binding Affimer proteins that inhibit RAS function and reveal a novel druggable SII/3 pocket.

41 citations

humanexperimental assay

𝕏 PostBluesky