Cancer BiologyPLoS PathogensPeer-reviewed
The Mitochondrial Ubiquitin Ligase MARCHF5 Cooperates with MCL1 to Inhibit Apoptosis in KSHV-Transformed Primary Effusion Lymphoma Cell Lines
Prasanth Viswanathan, Justine R Bersonda, Jackson Gill…·Mark Manzano
This study identifies a genetic interaction between MCL1 and MARCHF5 in PEL cells, showing that MARCHF5 promotes cell survival by degrading NOXA, an antagonist of MCL1.
DOI 10.1371/journal.ppat.1014665