Author

Ajinkya Patil

Broad InstituteORCID 0000-0003-1080-1146Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetic & Genomic Medicine· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Cigall KadochiD· 2 shared Aakaanksha MaddineniiD· 1 shared Ajay NadigiD· 1 shared Akshay Sankar· 1 shared Alexander Wang YingiD· 1 shared Anders Dupont BørglumiD· 1 shared Bengul GokbayrakiD· 1 shared Dana S. NeeliD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Cigall KadochORCID

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3 papers

Recent·Most cited

Molecular BiologyNature GeneticsPeer-reviewedOct 20, 2025

Shifted assembly and function of mSWI/SNF family subcomplexes underlie targetable dependencies in dedifferentiated endometrial carcinomas

Jessica D. St. Laurent, Grace Dydian Xu, Alexander Wang Ying…·Cigall Kadoch

This study identifies shifted mSWI/SNF subcomplex stoichiometry in DDEC/UEC cancers and shows that SMARCA4/2 inhibitors reduce tumor growth and synergize with chemotherapy.

4 citations

humanDNA methylation

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Genetic & Genomic MedicinemedRxivPreprintJul 1, 2025

Functional consequences of genetic risk for neuropsychiatric conditions at chr22q

Ajay Nadig, Matthew Tegtmeyer, Ajinkya Patil…·Elise Robinson

The paper identifies chr22q as a regulatory hub where genetic risk for neuropsychiatric conditions is associated with coordinated gene expression downregulation in brain tissue.

1 citation

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintSep 23, 2024

Cytotoxicity of Activator Expression in CRISPR-based Transcriptional Activation Systems

Aakaanksha Maddineni, Ziyan Liang, Shreya Jambardi…·Eva Gottwein

This study shows that CRISPRa systems can cause cytotoxicity, limiting their use in research and genetic screens.

3 citations

humanCRISPR screen

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