Author

Zizhuo Sha

Fudan University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Chunli YangiD· 3 shared Feihong YangiD· 3 shared Zhejun XuiD· 3 shared Zhengang YangiD· 3 shared Zhuangzhi ZhangiD· 3 shared Jialin Li· 2 shared Tongye Fu· 2 shared Wenhui ZhengiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersDevelopmental Biology

Chunli YangORCID

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3 papers

Recent·Most cited

ERK signaling integrates multiple mechanisms to drive cortical evolutionary expansion

Tongye Fu, Zhuangzhi Zhang, Wenhui Zheng, Chunli Yang, Zizhuo Sha, Danyu Han, Jialin Li, Feihong Yang, Jingzhe Yu, Zhenmeiyu Li, You Yan, Tong Ma, Weiwei Li, Guoping Liu, Xiaolei Song, , Zhengang Yang

The paper shows that enhanced ERK signaling in human cortical radial glia drives cortical neuron expansion through interactions with PKA signaling and cell cycle regulation.

bioRxiv · Jul 28, 2026 · PreprintDevelopmental Biology

Mutant FGFR3 restricts bone yet expands cortex via ERK-mediated self-repression

Zhuangzhi Zhang, Zhejun Xu, Tongye Fu, Wenhui Zheng, Zizhuo Sha, Chunli Yang, Feihong Yang, Jialin Li, Jing Ding, Zhengang Yang

This paper shows that FGFR3 mutations cause bone shortening and brain overgrowth through ERK-mediated self-repression in different tissues.

bioRxiv · Feb 6, 2026 · PreprintDevelopmental Biology

Integrated ERK, PKA, YAP/TAZ, and SHH Signaling Drives Cortical Lineage Diversification and Evolutionary Expansion

Zhuangzhi Zhang, Zhejun Xu, Tao Fu, Jialin Li, Feihong Yang, Chunli Yang, Wenhui Zheng, Zizhuo Sha, Yanjing Gao, Mengge Sun, Zhenmeiyu Li, Jing Ding, Xiaosu Li, Zhengang Yang

This study identifies how ERK, PKA, YAP/TAZ, and SHH signaling integrate to drive cortical lineage diversification and evolutionary expansion in the human cerebral cortex.

Advanced Science · Nov 12, 2025Peer-reviewedDevelopmental Biology