Genetic modification of primary airway epithelial cell cultures defines MX1 as a barrier for zoonotic influenza A viruses in the human respiratory epithelium
Karen Stevers, Blandina Isabel Oliveira Esteves, Étori Aguiar Moreira…·Ronald Dijkman
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University of BernORCID 0000-0003-0320-2743Unclaimed ORCID profile · follow to get notified of new preprints
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4 papers
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Karen Stevers, Blandina Isabel Oliveira Esteves, Étori Aguiar Moreira…·Ronald Dijkman
Karen Stevers, Sarah Jordi, Blandina Isabel Oliveira Esteves, Ronald Dijkman
This paper describes protocols for generating genetically modified airway epithelial cell cultures to study virus-host interactions of emerging respiratory viruses.
Simone Leoni, Isabel Schultz-Pernice, Zuzana Krátka…·Stephen L. Leib
This study evaluates remdesivir and bemnifosbuvir's efficacy against TBEV in vitro and ex vivo, finding dose-dependent viral load reduction with notable cytotoxicity for remdesivir.
Rosanne W. Koutstaal, Amadeo Munoz-Garcia, Nadine Ebert…·Puck B. van Kasteren
This study shows RSV NS1 supports viral replication by inhibiting IFN production and chemokine secretion in nasal epithelial cells, using an ALI model for vaccine assessment.