Genetic modification of primary airway epithelial cell cultures defines MX1 as a barrier for zoonotic influenza A viruses in the human respiratory epithelium
Karen Stevers, Blandina Isabel Oliveira Esteves, Étori Aguiar Moreira…·Ronald Dijkman
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University of BernORCID 0000-0003-2976-5325Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Karen Stevers, Blandina Isabel Oliveira Esteves, Étori Aguiar Moreira…·Ronald Dijkman
Étori Aguiar Moreira, Samuel Constant, Charlene Constant…·Gert Zimmer
This study shows that a bovine-derived H5N1 virus replicates efficiently in human nasal epithelial cells at both 37°C and 33°C, with specific mutations enhancing replication at lower temperatures.
Demeter Túrós, Lollija Gladiseva, Marius Alexandru Botos…·Étori Aguiar Moreira
X-Pression reconstructs 3D expression signatures from volumetric microcomputed tomography data, demonstrating its utility in analyzing vaccine efficacy and viral replication in mouse lungs.