Bemnifosbuvir and remdesivir inhibit tick-borne encephalitis virus infection in complementary in vitro and ex vivo disease models
Simone Leoni, Isabel Schultz-Pernice, Zuzana Krátka, Lucie Freiholz, Amal Fahmi, Teodora David, Antoinette Golomingi, Fabian Blank, Michaela Beránková, Milan Dejmek, Denis Grandgirard, Ronald Dijkman, Daniel Růžek, Luděk Eyer, Marco P. Alves, Stephen L. Leib
This study evaluates remdesivir and bemnifosbuvir's efficacy against TBEV in vitro and ex vivo, finding dose-dependent viral load reduction with notable cytotoxicity for remdesivir.
Antiviral Research · May 24, 2026Peer-reviewedMicrobiology