Author

Zhizhong Zheng

University of RochesterORCID 0000-0003-0352-4806Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Andrei SeluanoviD· 2 shared Valentin Pavlovich VolobaeviD· 2 shared Vera A. GorbunovaiD· 2 shared Alexander V. GalazyukiD· 1 shared Cheyenne RechsteineriD· 1 shared Denis FirsanoviD· 1 shared Dominic AlcockiD· 1 shared Emma C. TeelingiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCell Biology

Andrei SeluanovORCID

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2 papers

Recent·Most cited

Cell BiologyNature CommunicationsPeer-reviewedMay 3, 2025

Limited Cell-Autonomous Anticancer Mechanisms in Long-Lived Bats

Fathima Athar, Zhizhong Zheng, Sébastien Riquier…·Vera A. Gorbunova

This study shows that bat fibroblasts require fewer oncogenic hits for malignant transformation compared to other long-lived mammals, suggesting reliance on non-cell autonomous tumor suppression mechanisms.

27 citationstop 2%

mousehuman

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Molecular BiologybioRxivPreprintMar 24, 2025

SIRT6 activator fucoidan extends healthspan and lifespan in aged wild-type mice

Seyed Ali Biashad, Eric C. Hillpot, Francesco Morandini…·Vera A. Gorbunova

This study shows that fucoidan, a seaweed-derived polysaccharide, extends healthspan and lifespan in aged mice by activating SIRT6, which reduces LINE1 retrotransposon activity and epigenetic aging.

5 citations

mouseexperimental assay

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