Author

Valentin Pavlovich Volobaev

University of RochesterORCID 0000-0001-7355-9882Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:rat· 1

Frequent Co-Authors

Andrei SeluanoviD· 2 shared Vera A. GorbunovaiD· 2 shared Zhizhong ZhengiD· 2 shared Alexander V. GalazyukiD· 1 shared Cheyenne RechsteineriD· 1 shared Denis FirsanoviD· 1 shared Dominic AlcockiD· 1 shared Emma C. TeelingiD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Andrei SeluanovORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Limited Cell-Autonomous Anticancer Mechanisms in Long-Lived Bats

Fathima Athar, Zhizhong Zheng, Sébastien Riquier, Max Zacher, Jinlong Y. Lu, Yang Zhao, Valentin Pavlovich Volobaev, Dominic Alcock, Alexander V. Galazyuk, Lisa Noelle Cooper, Tony Schountz, Lin‐Fa Wang, Emma C. Teeling, Andrei Seluanov, Vera A. Gorbunova

This study shows that bat fibroblasts require fewer oncogenic hits for malignant transformation compared to other long-lived mammals, suggesting reliance on non-cell autonomous tumor suppression mechanisms.

Nature Communications · May 3, 2025Peer-reviewedCell Biology

SIRT6 activator fucoidan extends healthspan and lifespan in aged wild-type mice

Seyed Ali Biashad, Eric C. Hillpot, Francesco Morandini, Cheyenne Rechsteiner, Victoria Paige, Gregory Tombline, Minseon Lee, Zhizhong Zheng, Yuan Liang, John C. Martinez, Natasha Sieczkiewicz, Zhihui Zhang, Valentin Pavlovich Volobaev, Denis Firsanov, Matthew A. Simon, , Vera A. Gorbunova

This study shows that fucoidan, a seaweed-derived polysaccharide, extends healthspan and lifespan in aged mice by activating SIRT6, which reduces LINE1 retrotransposon activity and epigenetic aging.

bioRxiv · Mar 24, 2025 · PreprintMolecular Biology