Katherine A. Fantauzzo

This study shows that PDGFR signaling is essential for postnatal development of perivascular fibroblasts in the brain.

This study shows that conditional ablation of PDGFRα and SHP2 in mouse neural crest cells leads to craniofacial defects, with SHP2 regulating PDGFR signaling both positively and negatively.

PDGFR/{beta} heterodimer binding to MYO1D promotes rapid internalization, inhibiting ERK1/2 phosphorylation and reducing cell proliferation.

This study shows PDGFRα signaling regulates Srsf3 binding to transcripts, affecting PI3K signaling and endosomal trafficking in craniofacial development.

This study identifies Srsf3 as a regulator of alternative RNA splicing downstream of PDGFRα signaling, which is critical for craniofacial development.

This study investigates the genetic interaction between Pdgfra and Pdgfrb in murine neural crest cells, showing their distinct roles in migration and proliferation during craniofacial development.