Jan M. Rodriguez Parkitna

This study examines the effect of preproenkephalin gene deletion on heart function in mice, finding no major changes in heart size or function under basal conditions but some reductions in filling and ejection rates.

This study investigates dopamine dynamics and dopaminoceptive circuits in the motor cortex during skilled forelimb movements in mice, showing their role in reinforcement learning.

This study shows that social reward in male mice decreases during mid-adolescence, mirroring human developmental patterns.

This paper introduces a framework combining point processes with reinforcement learning to analyze individual and group learning in mice, finding that group effects are twice as strong as individual learning.

The paper introduces a reinforcement learning model to study social influence in mice, revealing how group structure and individual learning strategies vary based on goal alignment and motivational states.

The paper shows that opioid receptor antagonists increase social conditioned place preference in early adolescent mice, suggesting developmental changes in social motivation mechanisms.

This study shows risperidone alters gene expression in specific brain regions of mice, with 21 of the affected genes linked to schizophrenia.

This study shows that adolescent mice show reduced reward sensitivity for social and food rewards but not cocaine, compared to adults, suggesting developmental changes in reward processing.

The paper examines L-DOPA-induced gene expression changes in the forebrain of mice with progressive dopaminergic neuron loss, identifying region-specific effects and novel genes involved in nonmotor PD symptoms.

The paper identifies a long 3' untranslated region in the primary Oprm1 transcript in mice, with additional variants expressed at lower levels.

The paper identifies distinct distributions and functions of dopamine receptor-expressing neurons in the motor cortex, showing D2+ neurons specifically affect skilled forelimb reaching.

This study identifies nonmotor symptoms linked to early dopaminergic neuron loss in a mouse Parkinson's disease model.

This study examines how L-DOPA affects gene expression in the frontal cortex of rats with unilateral dopaminergic lesions, identifying bilateral gene expression changes and non-specific drug effects.

This study shows that knocking down mu and delta opioid receptors in dopamine receptor D1-expressing neurons does not impair reward sensitivity or related behaviors.