Author

Cole J.T. Lewis

Yale UniversityORCID 0000-0003-0385-2260Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Shivani Bhandarkar· 2 shared Wendy V. GilbertiD· 2 shared Andrei Stanciu· 1 shared Austin S. DraycottiD· 1 shared Carson C. ThoreeniD· 1 shared Colin Echeverría AitkeniD· 1 shared Danni Jin· 1 shared Jaswinder KauriD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersSystems Biology

Shivani Bhandarkar

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2 papers

Recent·Most cited

Systems BiologyRNAPeer-reviewedDec 3, 2024

Cellular translational enhancer elements that recruit eukaryotic initiation factor 3

Jiří Koubek, Jaswinder Kaur, Shivani Bhandarkar…·Wendy V. Gilbert

The paper identifies a specific 5'-UTR motif, AMAYAA, that eIF3 binds to, enhancing translation under stress conditions.

7 citations

yeastbulk RNA-seq

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Systems BiologybioRxivPreprintFeb 28, 2024

Quantitative profiling of human translation initiation reveals regulatory elements that potently affect endogenous and therapeutically modified mRNAs

Cole J.T. Lewis, Li Xie, Shivani Bhandarkar…·Wendy V. Gilbert

The paper quantifies translation initiation on human mRNAs, identifies regulatory elements with potent effects, and shows that N1-methylpseudouridine enhances translation in specific 5' UTRs.

5 citations

humanmetagenomics

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