MicrobiologymBioPeer-reviewed
Host GPCR-cAMP signaling balances Gαs and Gαi activity to control intracellular Brucella infection
1 citationtop 5%
Author
James E. Kirby
Beth Israel Deaconess Medical CenterORCID 0000-0003-0392-4500Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2022-2026 · peak 3/yrCo-Author Collaboration Network
10 top collaborators · 16 mutual co-author linksFocal author (center)Selected co-authorORCID co-authorUnlinked name
Curved chords = mutual co-authorship2 shared papersMicrobiology
Yanqin HuangORCID
6 papers
Recent·Most cited
- MicrobiologybioRxivPreprint
Genome-wide identification of metabolic and regulatory determinants of intracellular growth in Brucella neotomae
This study identifies metabolic and regulatory factors essential for Brucella neotomae intracellular growth using Tn-seq and genetic analysis.
DOI 10.64898/2026.04.05.716554 - MicrobiologyJournal of Clinical MicrobiologyPeer-reviewed
Poloxamer dilution as an on-demand alternative to agar dilution-based antimicrobial susceptibility testing
Matthew T. J. Uy, Andrea Kirmaier, Lindsey Rudtner…·James E. Kirby
This paper introduces poloxamer dilution as an on-demand alternative to agar dilution for antimicrobial susceptibility testing, showing comparable performance for fosfomycin against gram-negative pathogens.
- MicrobiologyJournal of Antimicrobial ChemotherapyPeer-reviewed
Enhanced Activity of Apramycin and Apramycin-Based Combinations Against Mycobacteroides abscessus
Yanqin Huang, Katherine A. Truelson, Isabella Stewart…·James E. Kirby
This study compares the in vitro activity of apramycin and other aminoglycosides against Mycobacteroides abscessus and related species, finding apramycin more potent than amikacin.
- MicrobiologyAntimicrobial Agents and ChemotherapyPeer-reviewed
Triple antimicrobial combinations with potent synergistic activity against M. abscessus
Yanqin Huang, Lucius Chiaraviglio, Ibidunni Bode-Sojobi, James E. Kirby
The paper tests triple antimicrobial combinations against M. abscessus isolates and finds synergistic activity in several combinations, with some sensitizing resistant isolates.
- GenomicsGenome MedicinePeer-reviewed
Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance
Rauf Salamzade, Abigail L. Manson, Bruce J. Walker…·Ashlee M. Earl
The paper develops a method to trace horizontal gene transfer and persistence of carbapenem resistance genes across bacterial species using genomic data from clinical isolates.