Author

Andrew T. Chen

Michael G. DeGroote Institute for Infectious Disease ResearchORCID 0000-0003-0396-9960Unclaimed ORCID profile · follow to get notified of new preprints

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Immunology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Art MarzokiD· 1 shared Jann Catherine Ang· 1 shared Jonathan Mapletoft· 1 shared Joshua J.C. McGrathiD· 1 shared Julia Avolio· 1 shared Kyle AmaraliD· 1 shared Martin R. StämpfliiD· 1 shared Matthew S. MilleriD· 1 shared

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2025-2025 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Art MarzokORCID

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1 paper

Recent·Most cited

ImmunologybioRxivPreprintSep 23, 2025

Senataxin is required for optimal class switch recombination to the immunoglobulin A isotype

Vithushan Surendran, Jonathan Mapletoft, Peter YF. Zeng…·Matthew S. Miller

This study shows that senataxin deficiency impairs class switch recombination to IgA in vitro, reduces IgA response to infection, and decreases IgA repertoire diversity in vivo.

DOI 10.1101/2025.09.23.678005

mousebulk RNA-seq

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