Matthew S. Miller

Acute viral infection accelerates ALS progression in SOD1G93A mice by inducing gliosis and metabolic dysregulation, which can be mitigated by anti-inflammatory or antiviral treatments.

This study shows that senataxin deficiency impairs class switch recombination to IgA in vitro, reduces IgA response to infection, and decreases IgA repertoire diversity in vivo.

This study shows that DNA aptamer nanomaterials can protect against diverse SARS-CoV-2 variants through respiratory mucosal administration, offering broad neutralization and superior protection compared to monoclonal antibodies.