Author

Travis L. Cossette

Jackson LaboratoryORCID 0000-0003-0398-5047Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:clustering· 1

Frequent Co-Authors

Gareth R. HowelliD· 3 shared Michael MacLeaniD· 3 shared Alaina M. ReaganiD· 2 shared Amanda A. HewesiD· 2 shared Cory A. DiemleriD· 2 shared Olivia J. MarolaiD· 2 shared Daniel A. SkellyiD· 1 shared Jonathan Nyandu KanyindaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersNeuroscience

Gareth R. HowellORCID

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3 papers

Recent·Most cited

GeneticsAlzheimer s & DementiaPeer-reviewedJul 31, 2025

Retinal vascular dysfunction in the Mthfr677C>T mouse model of cerebrovascular disease

Alaina M. Reagan, Michael MacLean, Travis L. Cossette, Gareth R. Howell

The paper examines retinal vascular changes in Mthfr677C>T mice, finding similarities to cerebrovascular changes in AD, suggesting retinal assessment as a potential biomarker.

4 citations

mouseproteomics

𝕏 PostBluesky

NeuroscienceMolecular NeurodegenerationPeer-reviewedJan 20, 2025

Genetic context modulates aging and degeneration in the murine retina

Olivia J. Marola, Michael MacLean, Travis L. Cossette…·Gareth R. Howell

This study examines retinal aging across nine genetically diverse mouse strains, identifying molecular aging signatures and validating WSB and NZO as models for retinal neurodegenerative diseases.

15 citationstop 4%

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 4, 2023

Metabolic syndrome in New Zealand Obese mice promotes microglial-vascular interactions and reduces microglial plasticity

Michael MacLean, Olivia J. Marola, Travis L. Cossette…·Gareth R. Howell

This study shows that metabolic syndrome in NZO mice reduces microglial plasticity and increases vascular interactions compared to B6J mice.

3 citations

mousebulk RNA-seq

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