Shank3 establishes AMPA receptor subunit composition at cerebellar mossy fiber-granule cell synapses and shapes regional microglia activation.
Rajaram Kshetri, Ben D Richardson
This study investigates how Shank3 loss affects cerebellar glutamatergic synapses and microglia activation, finding increased AMPAR function and altered microglia morphology in Shank3 KO mice.