Author

Rafael T. M. de Rosales

King's College LondonORCID 0000-0003-0431-0535Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:imaging· 2 Organism:mouse· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Amaia Carrascal-MiniñoiD· 3 shared Aishwarya MishraiD· 2 shared Kavitha SunasseeiD· 2 shared Stéfan HalbherriD· 2 shared Truc PhamiD· 2 shared Abdullah Aslam KhaniD· 1 shared Anne Worthington· 1 shared Antonios N. PouliopoulosiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersBioengineering

Amaia Carrascal-MiniñoORCID

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3 papers

Recent·Most cited

BioengineeringJournal of Controlled ReleasePeer-reviewedSep 1, 2025

PET imaging for non-invasive monitoring of 89Zr-Talidox delivery to the brain following focused ultrasound-mediated blood-brain barrier opening

Aishwarya Mishra, Chris Payne, Amaia Carrascal-Miniño…·Rafael T. M. de Rosales

This study uses PET imaging to monitor Talidox delivery to the brain after focused ultrasound opens the blood-brain barrier, showing a 14-fold increase in brain uptake.

6 citations

mouseimaging

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BioengineeringbioRxivPreprintJun 17, 2025

A translatable evaluation tool to study the biodistribution of clinically-available doxorubicin liposomes: PET imaging of Zr-Talidox

Amaia Carrascal-Miniño, Aishwarya Mishra, Peter J. Gawne…·Rafael T. M. de Rosales

This paper validates a radiolabeling method using 89Zr to enable PET imaging of doxorubicin liposomes, showing stable biodistribution and clinical translatability.

2 citations

mouseimaging

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ImmunologybioRxivPreprintJun 16, 2025

Characterisation of distinct senescent-like T cell populations during healthy and unhealthy ageing

Conor Garrod-Ketchely, Lauren A. Callender, Johannes Schroth…·Siân M. Henson

This study identifies a distinct senescent-like CD8 TEMRA cell population in older individuals with type 2 diabetes, linked to metabolic inflammation and impaired immune function.

1 citation

humanflow cytometry

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