Author

Bobbie Pelham‐Webb

Weill Cornell MedicineORCID 0000-0003-0437-8206Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:mouse· 3 Research Focus:spatial domain detection· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2

Frequent Co-Authors

Effie ApostolouiD· 3 shared Alexander PolyzosiD· 2 shared Andreas KloetgeniD· 2 shared Aristotelis TsirigosiD· 2 shared Jiexi LiiD· 2 shared Abhishek SinhaiD· 1 shared Alejandra Laguillo-DiegoiD· 1 shared Alexandros PertsinidisiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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3 shared papersMolecular Biology

Effie ApostolouORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintFeb 13, 2025

Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion

UkJin Lee, Alejandra Laguillo-Diego, Wilfred Wong…·Effie Apostolou

This study shows that cohesin depletion affects locus- and differentiation-specific transcriptional activation and regulatory interactions in mouse ESCs, with some loops and genes being more sensitive than others.

3 citations

mouseChIP-seq

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Developmental BiologyDevelopmental CellPeer-reviewedOct 27, 2021

A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus

Boaz E. Aronson, Laurianne Scourzic, Veevek Shah…·Effie Apostolou

The paper identifies a bipartite imprinting control region at the Dlk1-Dio3 locus that maintains imprint stability through allele-specific regulation of DNA methylation and chromatin structure.

30 citations

mouseDNA methylation

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Molecular BiologyMolecular CellPeer-reviewedMar 18, 2021

Mitotic retention of H3K27 acetylation promotes rapid topological and transcriptional resetting of stem cell-related genes and enhancers upon G1 entry

Bobbie Pelham‐Webb, Alexander Polyzos, Luke Wojenski…·Effie Apostolou

This study shows that H3K27 acetylation retention during mitosis accelerates transcriptional and topological resetting of stem cell genes in mouse pluripotent stem cells upon G1 entry.

124 citationstop 2%

mouseChIP-seq

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