Author

Alexandros Pertsinidis

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-7855-2794Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Jieru LiiD· 2 shared Lingling ChengiD· 2 shared Zhangli NiiD· 2 shared Alejandra Laguillo-DiegoiD· 1 shared Bobbie Pelham‐WebbiD· 1 shared Christina S. LeslieiD· 1 shared Effie ApostolouiD· 1 shared Hiroaki OhishiiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Jieru LiORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintDec 31, 2025

NIPBL-mediated 3D genome folding translates enhancer priming into gene activation and safeguards lineage fidelity during embryonic transitions

Zhangli Ni, Xiaohui Ma, Stephanie Do…·Alexandros Pertsinidis

This study shows NIPBL-mediated 3D genome folding is essential for enhancer-promoter communication and maintaining lineage fidelity during embryonic development.

2 citations

mousebulk RNA-seq

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Molecular BiologybioRxivPreprintFeb 13, 2025

Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion

UkJin Lee, Alejandra Laguillo-Diego, Wilfred Wong…·Effie Apostolou

This study shows that cohesin depletion affects locus- and differentiation-specific transcriptional activation and regulatory interactions in mouse ESCs, with some loops and genes being more sensitive than others.

3 citations

mouseChIP-seq

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Molecular BiologyNature CommunicationsPeer-reviewedDec 20, 2022

STREAMING-tag system reveals spatiotemporal relationships between transcriptional regulatory factors and transcriptional activity

Hiroaki Ohishi, Seiru Shimada, Satoshi Uchino…·Hiroshi Ochiai

The paper develops a STREAMING-tag system to study spatiotemporal relationships between transcriptional factors and activity in living cells.

40 citations

mouseexperimental assay

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