Author

Alejandra Laguillo-Diego

Weill Cornell MedicineORCID 0000-0003-2724-7890Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Developmental Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

Effie ApostolouiD· 3 shared Kritika KasliwaliD· 2 shared Matthias StadtfeldiD· 2 shared Simone SidoliiD· 2 shared UkJin LeeiD· 2 shared Abigail LidoskiiD· 1 shared Alexander PolyzosiD· 1 shared Alexandros PertsinidisiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Effie ApostolouORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 10, 2026

KAT6 and KAT7 actively maintain mitotic chromatin composition and acetylation to preserve developmental competence

Alejandra Laguillo-Diego, UkJin Lee, Xiao Liu…·Effie Apostolou

This study shows KAT6 and KAT7 maintain mitotic chromatin acetylation and composition, supporting postmitotic transcriptional memory and developmental competence in stem cells.

DOI 10.64898/2026.11.07.765049

mousehuman

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Developmental BiologybioRxivPreprintOct 12, 2026

Developmental rewiring of EHMT1 function during human cortical neurogenesis

Kritika Kasliwal, Kaushiki Chatterjee, Vittoria Dickinson Bocchi…·Matthias Stadtfeld

This study shows EHMT1's functional rewiring during human cortical neurogenesis, revealing its shift from restraining pluripotency to supporting neuronal programs and its resilience to prolonged depletion.

DOI 10.64898/2026.10.09.757098

humanbulk RNA-seq

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Molecular BiologybioRxivPreprintFeb 13, 2025

Post-mitotic transcriptional activation and 3D regulatory interactions show locus- and differentiation-specific sensitivity to cohesin depletion

UkJin Lee, Alejandra Laguillo-Diego, Wilfred Wong…·Effie Apostolou

This study shows that cohesin depletion affects locus- and differentiation-specific transcriptional activation and regulatory interactions in mouse ESCs, with some loops and genes being more sensitive than others.

3 citations

mouseChIP-seq

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