Developmental BiologyJournal of the American Society of NephrologyPeer-reviewed
Reduced nephron endowment in the common Six2-TGCtg mouse line is due to Six3 misexpression by aberrant enhancer-promoter interactions in the transgene
Alison J. Perl, Han Liu, Matthew R. Hass…·Raphael Kopan
The paper identifies that reduced nephron numbers in Six2-TGCtg mice result from Six3 misexpression due to aberrant enhancer-promoter interactions in the transgene.
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