Leiv Otto Watne

The paper identifies a subset of older adults with stable memory performance over time, linking this stability to brain structure and showing it is often transient rather than consistent.

This study examines how brain volume differences in adults are stable from young adulthood or change with age, using MRI data from 8,311 individuals.

Bivariate GSA-MiXeR is a tool that models genetic correlations between two traits to identify genomic regions associated with psychiatric and neurodegenerative disorders using single-cell RNA sequencing data.

This study investigates the relationship between brain atrophy and memory decline in aging using longitudinal data, finding a nonlinear association that intensifies with age and is influenced by APOE ε4 carriership.

This study assesses the reliability of structural brain change in cognitively healthy adults over time, finding that longer follow-up periods significantly improve reliability compared to increasing observation frequency.

The paper identifies subtypes of brain structural changes in aging and links them to cognitive decline and Alzheimer's disease biomarkers using MRI data.

The paper investigates the effects of short sleep on brain structure and cognitive function, finding that short sleepers without daytime tiredness have larger brain volumes but slightly lower cognitive scores.

This study examines the relationship between sleep duration and brain structure using MRI data, finding that 6.8 hours of sleep is associated with the most favorable brain outcomes, with genetic analyses suggesting homeostatic regulation of sleep duration.

This study shows genetic risk for Alzheimer's disease affects hippocampal volume throughout life in a healthy population.

This study investigates how acute inflammation disrupts energy metabolism in mice and humans, linking it to behavioral and cognitive impairments like hypoactivity, delirium, and impaired cognition.

The paper examines the relationship between self-reported sleep parameters and cortical thinning in aging, finding associations with specific brain regions but not with memory decline or amyloid-β accumulation.

The paper examines how self-reported sleep relates to hippocampal atrophy across adulthood using data from the Lifebrain consortium and UK Biobank, finding that worse sleep is linked to faster hippocampal volume loss over time.

The paper examines the relationship between sleep problems and amyloid deposition in cortical regions with high HOMER1 expression in older adults, finding a stronger link in younger participants and regions with high HOMER1 expression.