Cristina Solé‐Padullés

Stable Individual Differences Dominate Adult Brain Volume Variation Until Later Life

This study examines how brain volume differences in adults are stable from young adulthood or change with age, using MRI data from 8,311 individuals.

Vulnerability to memory decline in aging. A mega-analysis of structural brain change.

This study investigates the relationship between brain atrophy and memory decline in aging using longitudinal data, finding a nonlinear association that intensifies with age and is influenced by APOE ε4 carriership.

Reliability of structural brain change in cognitively healthy adult samples.

This study assesses the reliability of structural brain change in cognitively healthy adults over time, finding that longer follow-up periods significantly improve reliability compared to increasing observation frequency.

Genome-wide QTL mapping across three tissues highlights several Alzheimer's and Parkinson's disease loci potentially acting via DNA methylation

The paper maps DNA methylation quantitative trait loci (meQTL) in three tissues and uses Mendelian randomization to link DNAm to Alzheimer's and Parkinson's disease risk.

Is short sleep bad for the brain? Brain structure and cognitive function in short sleepers

The paper investigates the effects of short sleep on brain structure and cognitive function, finding that short sleepers without daytime tiredness have larger brain volumes but slightly lower cognitive scores.

Sleep duration and brain structure - phenotypic associations and genotypic covariance

This study examines the relationship between sleep duration and brain structure using MRI data, finding that 6.8 hours of sleep is associated with the most favorable brain outcomes, with genetic analyses suggesting homeostatic regulation of sleep duration.

Education and income show heterogeneous relationships to lifespan brain and cognitive differences across European and US cohorts

The paper examines how education and income relate to brain and cognitive differences across European and US cohorts, finding heterogeneous effects and stronger associations in US samples.

Self-Reported Sleep Relates to Microstructural Hippocampal Decline in β-Amyloid Positive Adults Beyond Genetic Risk

This study finds that worse self-reported sleep relates to faster hippocampal microstructural decline in β-amyloid positive adults, independent of genetic risk.

The genetic organization of subcortical volumetric change is stable throughout the lifespan

This paper identifies stable developmental clusters of subcortical volumetric change across the lifespan and shows genetic organization within these clusters.

Multifocal tDCS modulates resting-state functional connectivity in older adults depending on induced electric field and baseline connectivity

This study shows that multifocal tDCS modulates resting-state connectivity in older adults, with effects dependent on electric field distribution and baseline connectivity.

Self-reported sleep problems are related to cortical thinning in aging but not memory decline and amyloid-β accumulation - results from the Lifebrain consortium

The paper examines the relationship between self-reported sleep parameters and cortical thinning in aging, finding associations with specific brain regions but not with memory decline or amyloid-β accumulation.

Self-reported sleep relates to hippocampal atrophy across the adult lifespan - results from the Lifebrain consortium

The paper examines how self-reported sleep relates to hippocampal atrophy across adulthood using data from the Lifebrain consortium and UK Biobank, finding that worse sleep is linked to faster hippocampal volume loss over time.