Evan N. Nicolai

This study demonstrates the feasibility of endovascular vagus nerve stimulation using electrodes in the internal jugular vein, showing that electrode positioning is critical for effective VN activation.

This paper demonstrates the use of intraoperative ultrasound to visualize pig vagus nerve fascicular organization (vagotopy) and improve cuff placement for vagus nerve stimulation.

The paper identifies specific neuroanatomical pathways causing off-target effects of vagus nerve stimulation in pigs and characterizes dose-response curves for on- and off-target effects.

The paper characterizes the anatomy of the cervical vagus nerve in domestic pigs, identifying structural features relevant to vagus nerve stimulation and comparing them across species.

This study shows that cervical vagus nerve stimulation increases cerebrospinal fluid penetration into the brain, suggesting potential clinical implications for CNS disorders.