Author
Salford Royal NHS Foundation TrustORCID 0000-0003-0496-6710Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Piyali Ganguli, Celia De Los Angeles Colomina Basanta, Amelia Acha‐Sagredo…·Jo Spencer
The paper investigates how CDKN2A and other 9p21 gene losses influence oesophageal cancer progression, finding context-dependent effects on survival and immune infiltration.
Syed Murtuza Baker, Aoibheann F. Mullan, Rachel E. Jennings…·Andrew D Sharrocks
The paper identifies a metaplastic precursor state in Barrett's oesophagus as a reversion to a fetal epithelial cell state, revealing HNF4A's role and GWAS SNPs in regulatory regions.
Lauri A. Aaltonen, Federico Abascal, Adam A. Abeshouse…·Johann Sebastian De Bono
This study identifies germline genetic variants influencing somatic mutation patterns in 2,642 cancer genomes across 39 cancer types.
Yuan Yuan, Young Seok Ju, Young-Wook Kim…·Mario Berríos
This study characterizes mitochondrial genomes in 2,700 cancer patients across 37 types using whole-genome sequencing and RNA-seq, revealing mutational patterns, truncating mutations, and nuclear transfer of mitochondrial DNA.
Sam Abujudeh, Sebastian S. Zeki, MCV van Lanschot…·Richard Calvin Turkington
The paper introduces conliga, a method for inferring high-resolution SCNA profiles from a low-cost and simple assay, addressing the need for affordable SCNA analysis in clinical settings.