Chad W. Smies

This study shows that old mice have difficulty updating existing memories in the hippocampus, but re-engaging the original memory engram can improve this ability.

This study investigates how sex and age affect diurnal memory oscillations, circadian rhythms, and Per1 expression in mice, finding sex has a greater impact than age on circadian patterns and memory performance.

This study shows that HDAC3 inhibition improves memory updating in old mice but impairs it in young mice, suggesting HDAC3 regulates memory update strength and expression balance.

This study identifies Per1 as a circadian gene that modulates memory consolidation in the dorsal hippocampus, showing diurnal effects on long-term memory performance in mice.