Author

Shoko Murakami

Pennsylvania State UniversityORCID 0000-0002-3458-8987Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Janine L. KwapisiD· 3 shared Alexandria R. McKenna· 2 shared Annie G. Defina· 2 shared Aswathy SebastianiD· 2 shared Chad A. BrunswickiD· 2 shared Chad W. SmiesiD· 2 shared Gretchen C. Pifer· 2 shared Trinity A. Wood· 2 shared

Activity by Year

2022-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersNeuroscience

Janine L. KwapisORCID

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3 papers

Recent·Most cited

Aging disrupts transcriptional programs for memory updating in the dorsal hippocampus and reveals a required role for Tent5a in reconsolidation

Chad A. Brunswick, Annie G. Defina, Trinity A. Wood, Aswathy Sebastian, Alexandria R. McKenna, Shoko Murakami, Pu-Hsun Chiu, Shannon M. Jordan, Gretchen C. Pifer, Istvan Albert, Janine L. Kwapis

The paper identifies Tent5a as a regulator of reconsolidation-mediated memory updating in the dorsal hippocampus and shows aging disrupts transcriptional programs involved in this process.

bioRxiv · Sep 14, 2026 · PreprintNeuroscience

Old mice fail to integrate a memory update into an existing hippocampal engram.

Chad A. Brunswick, Annie G. Defina, Trinity A. Wood, Derek J. Baldwin, Alexandria R. McKenna, Avery R. Sicher, Cyrus Marwaha, Dakota F. Brockway, Shoko Murakami, Gretchen C. Pifer, Chad W. Smies, Nicole A. Crowley, Janine L. Kwapis

This study shows that old mice have difficulty updating existing memories in the hippocampus, but re-engaging the original memory engram can improve this ability.

bioRxiv · Jun 26, 2026 · PreprintNeuroscience

The clock gene Per1 expression may exert diurnal control over hippocampal memory consolidation

Lauren Bellfy, Chad W. Smies, Alicia R. Bernhardt, Kasuni K. Bodinayake, Aswathy Sebastian, Emily M. Stuart, Destiny S. Wright, Chen-Yu Lo, Shoko Murakami, Hannah M. Boyd, Megan J. von Abo, Istvan U. Albert, Janine L. Kwapis

This study identifies Per1 as a circadian gene that modulates memory consolidation in the dorsal hippocampus, showing diurnal effects on long-term memory performance in mice.

bioRxiv · Oct 11, 2022 · PreprintNeuroscience