Author

Gretchen C. Pifer

Pennsylvania State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Animal Behavior & Cognition· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:behavioral assay· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Janine L. KwapisiD· 3 shared Alexandria R. McKenna· 2 shared Annie G. Defina· 2 shared Chad A. BrunswickiD· 2 shared Chad W. SmiesiD· 2 shared Shoko MurakamiiD· 2 shared Trinity A. Wood· 2 shared Achintya Perumal· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersNeuroscience

Janine L. KwapisORCID

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Author profile →

3 papers

Recent·Most cited

Aging disrupts transcriptional programs for memory updating in the dorsal hippocampus and reveals a required role for Tent5a in reconsolidation

Chad A. Brunswick, Annie G. Defina, Trinity A. Wood, Aswathy Sebastian, Alexandria R. McKenna, Shoko Murakami, Pu-Hsun Chiu, Shannon M. Jordan, Gretchen C. Pifer, Istvan Albert, Janine L. Kwapis

The paper identifies Tent5a as a regulator of reconsolidation-mediated memory updating in the dorsal hippocampus and shows aging disrupts transcriptional programs involved in this process.

bioRxiv · Sep 14, 2026 · PreprintNeuroscience

Old mice fail to integrate a memory update into an existing hippocampal engram.

Chad A. Brunswick, Annie G. Defina, Trinity A. Wood, Derek J. Baldwin, Alexandria R. McKenna, Avery R. Sicher, Cyrus Marwaha, Dakota F. Brockway, Shoko Murakami, Gretchen C. Pifer, Chad W. Smies, Nicole A. Crowley, Janine L. Kwapis

This study shows that old mice have difficulty updating existing memories in the hippocampus, but re-engaging the original memory engram can improve this ability.

bioRxiv · Jun 26, 2026 · PreprintNeuroscience

Age and Sex Influence Diurnal Memory Oscillations, Circadian Rhythmicity, and Per1 Expression

Lauren Bellfy, Gretchen C. Pifer, Megan J. von Abo, Chad W. Smies, Alicia R. Bernhardt, Achintya Perumal, Marilyn Jackson, Janine L. Kwapis

This study investigates how sex and age affect diurnal memory oscillations, circadian rhythms, and Per1 expression in mice, finding sex has a greater impact than age on circadian patterns and memory performance.

bioRxiv · Jul 24, 2025 · PreprintAnimal Behavior & Cognition